Supramolecular Soft Matter Structures for Biomedical Applications
Miryam Criado Gonzales
POLYMAT Donostia-San Sebastian, Spain
23/11/2021, 10h30
ICS : amphitheater Henri Benoit
Zoom : https://cnrs.zoom.us/j/91044979572?pwd=RzIyTTNwZGxtZ2NFengxMHlxZEtxUT09
Meeting ID : 910 4497 9572
Code : semi23
Abstract.
Molecular self-assembly plays a key role in the development of tailor-made materials for biomedical applications. In this regard, natural polymers, which possess inherent biocompatibility, biodegradability, and non-toxicity, and more recently peptides, whose biological properties can be tailored by the sequenced defined chemical structure, have gained increasing attention. These two kind of soft materials are able to self-assemble in a controlled manner driven by intermolecular, i.e., van der Waals, hydrogen bonding, and/or hydrophobic intramolecular forces, leading to micro- and nano-structured platforms with different functionalities. Considering that the final biological properties will be highly influenced by the physical-chemical characteristics of the engineered materials, it becomes necessary to stablish a correlation between physics, chemistry, material science, biology, and medicine for the successful biomaterial implementation. Herein the design, fabrication and characterization of different supramolecular soft materials based on natural polymers and peptides will be
presented. Besides, the incorporation of nanoparticles and specific drugs within the polymer/peptide assemblies to tune the final properties of these materials to be employed for drug delivery, magnetic hyperthermia therapies, and tissue engineering applications will also be addressed.
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